Opening batsman Aiden Markram is set to make his international debut in the first Test against Bangladesh, which starts from September 28 in Potchefstroom. South Africa have also recalled seam-bowling allrounder Wayne Parnell to the 13-member squad for the first match, with Vernon Philander, Chris Morris and Dale Steyn all ruled out due to injury.
Markram and seamer Andile Phehlukwayo are the only two uncapped players in the squad. Both were part of the Test side during South Africa's tour of England earlier this year but did not get a game.
Nineteen-year-old Lions allrounder Willem Mulder has been invited as cover for Parnell, who will undergo a fitness test next week. If Parnell is fit, Mulder will return to the Lions team for the Sunfoil Series.
SA squad for first Test: Faf du Plessis (capt), Hashim Amla, Temba Bavuma, Theunis de Bruyn, Quinton de Kock, Dean Elgar, Keshav Maharaj , Aiden Markram, Morne Morkel, Duanne Olivier, Wayne Parnell, Andile Phehlukwayo, Kagiso Rabada