Week 5 is being branded a "Top 10 Throwdown" with three AP Top 10 matchups in the same week for the first time since 2002. Those games feature contenders in the ACC, Pac-12 and Big Ten, while the other two Power 5 conferences also boast a number of season-defining games for preseason conference favorites.
With the help of ESPN's Football Power Index (FPI), we'll break down and project the best games of Week 5. As a reminder, FPI's game projections account for team strength, game site, distance traveled and rest. Through three weeks, the FPI favorite has won 78 percent of FBS games, including 69 percent (22-10 record) of the top-tier games projected in this column.