Indianapolis Colts DL Kendall Langford will miss the first game of his NFL career

The Colts will be minus one regular defensive starter Sunday but will welcome one offensive starter back.

Defensive lineman Kendall Langford will miss the first game of his NFL career when the Colts face the Chiefs, but receiver Donte Moncrief will play for the first time since Week 2. Langford suffered a setback on the knee he had surgery on in early August.

"He's been battling through that thing and just never really got right," coach Chuck Pagano said Friday. "He's a tough, tough guy. He's an ironman. He's a warrior. He wants to play. His teammates know that. Finally we just said, lets shut him down for a little bit and get that thing totally healed, calmed down to where he can get back to playing winning football."

Langford had surgery on his knee on Aug. 8 and returned in time to extend his consecutive games played streak to 128. Pagano said he doesn't have a timetable on when Langford, who has 10 tackles this season, will be back.

Moncrief will be back for the first time since he injured his shoulder against the Denver Broncos in Week 2.

"We haven't had Donte for quite a while and it has hurt us," Colts offensive coordinator Rob Chudzinski said. "It will be good to have him back in the mix." The return of Moncrief and Phillip Dorsett means quarterback Andrew Luck will have his top three receivers at his disposal against the Chiefs.

Besides Langford, the Colts have also ruled out defensive lineman Henry Anderson (knee), tight end Dwayne Allen (ankle), Curt Maggitt (ankle), offensive lineman Jack Mewhort (tricep) and receiver Chester Rogers (hamstring/foot) for Sunday's game.