4:05 p.m. ET | CBS
Matchup rating: 38.9 | Spread: MIA -2.5 (48)
What to watch for: It's Tua Tagovailoa (No. 5 pick in 2020 draft) vs. Justin Herbert (No. 6), and though both players may say the right things this week, it's in a competitor's nature to want to outduel one of the other top QBs in his class. Herbert got a head start, beginning his career in Week 2 and throwing 17 TDs to just five interceptions. But Tagovailoa heads into his third start with the advantage in wins (2-0 vs. 1-6), and he's coming off a tantalizing performance against Kyler Murray's Cardinals. Quite a duel. -- Cameron Wolfe
Bold prediction: Chargers edge rusher Joey Bosa will return and have six pressures against Tagovailoa. He missed last week's game in concussion protocol. -- Shelley Smith
Stat to know: All six of the Chargers' losses this season have been in one-score games, tied for the most such losses within a team's first eight games in NFL history, per the Elias Sports Bureau (1944 Brooklyn Tigers, 1983 Buccaneers and 2015 Ravens).
What to know for fantasy: Since making his debut in Week 2, Herbert ranks as QB4 on a per game basis (24.3). He's top-10 at the position in rushing yards, passing yards and fantasy points per pass attempt. See Week 10 rankings.
Betting nugget: Miami has covered in four consecutive games, is 4-1 ATS as a home favorite since the start of the 2018 season and is 15-5 ATS since its Week 5 bye last season -- the best mark in the league. Read more.
Smith's pick: Chargers 27, Dolphins 23
Wolfe's pick: Dolphins 27, Chargers 23
FPI prediction: MIA, 64.5% (by an average of 5.0 points)
Matchup must-reads: Ballage hoping to build on banner debut with Chargers ... Dolphins' Tagovailoa reflects on one year since hip injury: 'Don't know if I'll ever be my old self' ... Dolphins WR Williams heads to injured reserve with foot injury