1 p.m. ET | CBS
Matchup rating: 48.6 | Spread: PIT -3.5 (45)
What to watch for: The Steelers have blitzed 64% of the time this season, the most in the NFL by a wide margin, according to ESPN Stats & Information. And Houston quarterback Deshaun Watson has the second-worst Total QBR against the blitz. Though Watson is the best signal-caller the Steelers have faced this season, look for the defense to still get a ton of pressure on the quarterback -- and from everywhere on the field. -- Brooke Pryor
Bold prediction: J.J. Watt and T.J. Watt will combine for five sacks. The Watt brothers usually have to check their phones after playing in a game to see how the other pass-rusher did, but on Sunday, they'll get to play in front of each other. In Week 2, the Watts combined for 4.5 sacks, which was the second-most by a set of brothers in a single day in NFL history. They'll top that on Sunday. -- Sarah Barshop
Stat to know: The Steelers have started 2-0 for the seventh time in the Ben Roethlisberger era (since 2004). They went on to make the playoffs in each of the last six instances (2005, 2007, 2008, 2010, 2016 and 2017). The Texans, on the other hand, are off to an 0-2 start for the third time in the last six seasons (2015 and 2018). But they recovered to make the playoffs in each of the previous two instances.
What to know for fantasy: Pittsburgh running back James Conner sure looked healthy in Week 2, as he piled up 97.2% of the Steelers' rushing yards. He was the only running back with a rate north of 85% last week. See Week 3 rankings.
Betting nugget: Pittsburgh is 7-13-2 ATS as a favorite since 2018. Read more.
Barshop's pick: Steelers 24, Texans 17
Pryor's pick: Steelers 27, Texans 17
FPI prediction: PIT, 66.3% (by an average of 5.9 points)
Matchup must-reads: Texans' run defense 'was bend but don't break, and we broke' ... Roethlisberger to set Steelers record for career games played ... Watt calls punch by Blacklock 'stupid, selfish' ... Texans' offensive struggles continue as unit searches for identity ... Blitzburgh is back: Steelers getting after QBs at a championship rate