Second legs of knockout rounds are always strange to bet. Because the aggregate score decides which team advances, incentives are often different than in typical games. Losing the second leg might be fine, if a team still advances on aggregate.
Plus, the possibility of extra time looms, if the aggregate score is tied, and away goals (the first tiebreaker) are even too. Also keep in mind that most available bets are for 90 minutes (plus stoppage time), though extra-time bets and to-qualify bets can be found as well. Know what you're betting!
With all that in mind, here are my plays for this week's second legs.
Odds courtesy of Caesars Sportsbook by William Hill.