Each week during the 2014 college football season I will offer my picks and scores for the biggest games in addition to a handful of other key matchups. Last week, my picks went 8-2 straight up and 5-5 against the spread.
Week 2 features perhaps the biggest nonconference game of the year between Michigan State and Oregon, an early key Pac-12 game between USC and Stanford and the final chapter in the storied Michigan-Notre Dame rivalry.
No. 7 Michigan State Spartans at No. 3 Oregon Ducks (-12)
Saturday at 6:30 p.m. ET
This is arguably the biggest nonconference game of the 2014 season matching two top-10 teams. The home team is 4-0 in the series, and the most recent meeting came in 1999, a 27-20 Michigan State win.
Wondering which side to take? Check out PickCenter and do your research before making that critical decision. PickCenter
Both teams are coming off dominating wins over FCS opponents last week. Oregon crushed South Dakota 62-13 highlighted by QB Marcus Mariota's four touchdowns in the first half. The Spartans' 45-7 win over Jacksonville State included an injury scare to QB Connor Cook, who was very efficient, going 12-of-13 for 285 yards and three touchdowns. It also saw their defense allow their first touchdown at home since Oct. 12 of last year, a span of 216 minutes of game time.