Shortly before kickoff, the Yellow Jackets announced that running back Jordan Mason and defensive lineman Curtis Ryans were among six players unavailable for the game. The school did not give a reason for their absence.
Mason led Georgia Tech with 899 yards rushing last season. He had 55 yards and a touchdown in a season-opening 16-13 victory at Florida State.
Ryans had two sacks and two forced fumbles against the Seminoles.
The Yellow Jackets also were without two other potential defensive starters, cornerback Tre Swilling and defensive end Antonneous Clayton, both of whom missed their second straight game with apparent injuries.