USC, OU, ND on upset alert

Collin Klein and Keenan Allen could both be involved in big upsets in Week 4. Getty Images/US Presswire

Every week during the season, Will Harris will check with the computers (using TeamRankings' win odds) and wiseguys to evaluate the upset possibilities in college football's most compelling games and give his picks for who'll come out on top.

We've cautioned against overvaluing USC this year, but we didn't see a loss coming this early. Stanford's win was the lead story of Week 3, but Virginia Tech was the biggest upset victim -- and the only ranked team, save BYU, to lose to an unranked opponent.

Upset Watch moves to 17-13 on the year after a poor 3-7 showing that saw us fall flat right along with the Hokies. We've got our eye on several live dogs in Week 4, including a Cal team that could send the Trojans into the tank for good.

Kansas State Wildcats at Oklahoma Sooners

Oklahoma is favored by 14 points
TeamRankings win odds for Kansas State: 20 percent

Bill Snyder hasn't had much success against former assistant Bob Stoops, but this year's Cats match up better than in years past. Kansas State's offense will seek to grind out yardage and control the clock, protecting its defense by limiting Oklahoma's offensive possessions. That plan has a good chance, because while the Sooners regain the services of a key defensive tackle this week, Mike Stoops' new charges are generally thin along the line and have shown weaknesses in run defense. Landry Jones may have fewer opportunities than he's had in any game of his career, and 40 minutes of time of possession for the visitors is not out of the question.