Some wild-card weekends are wilder than others. The fact that the Los Angeles Rams, Jacksonville Jaguars, Tennessee Titans and Buffalo Bills are playing this weekend suggests that it's not really 2018 but more like a step back in time to January 2000.
This kind of uncertainty and lack of playoff experience could lead to some wild results, but that doesn't mean you should automatically trust Super Bowl starters such as Matt Ryan, Cam Newton and Drew Brees. The new teams know how rare these opportunities are, and some of the best defenses in the league will play this weekend. If you want fantasy points, focus on the Titans-Chiefs game above all.
Here are the best and worst fantasy matchups for the wild-card round:
(Note: References to defensive rankings are based on Football Outsiders' DVOA metric, explained here.)