Fantasy football waiver wire for NFL Week 4: RB replacements among top pickups

There are a bunch of different things in the conversation for being the absolute best part about fantasy football. In fact, there are far too many to list here. However, there is one thing that is the far and away the worst -- injuries.

Injuries stink. They are wretched. There's no sugarcoating it. No matter the player, an injury is an injury and a completely disheartening situation.

On Thursday night, we saw an injury to the most high-profile player in fantasy football, Christian McCaffrey. A strained hamstring will keep him out for some period of time, although the specific timetable for his potential return remains uncertain.

While those who currently roster McCaffrey are unquestionably disappointed that their best player will not be available for the near future, here's your reminder that no matter how disappointed you are about your fantasy team, the player himself is exponentially more disappointed to not be on the field. Don't vent your disappointment at them -- ever!

We'll keep tabs on the timeline for the McCaffrey injury and follow along with how the Carolina Panthers divide his workload amongst the rest of the backfield. As to who we think gets first crack at the almost assuredly temporary starting gig there, read on! The identity of that individual leads our Week 4 ESPN Fantasy waiver-wire conversation below.

Note: All players on this column are available in at least 50% of leagues on ESPN.com.