Fantasy football last-minute pickups for NFL Week 10: Tua Tagovailoa, Darnell Mooney and more

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The roster percentages for this column are updated every Friday morning, and any players from Thursday's Colts-Titans game have been taken out.

Each week of the NFL season, we will identify fantasy football waiver-wire pickups specifically for those of you looking for streaming options in deeper formats (including IDP leagues). These are players available in a majority of ESPN Fantasy leagues who have enticing matchups in the week ahead that make them worthy of consideration for your lineup.

While you might notice some overlap with Field Yates' pickup column that publishes on Mondays, an important distinction is that the options mentioned in this column are focused solely on this week's matchup and not the players' values for the remainder of the season.

Do you need replacement options for injured players or those on a bye week? Or are you merely dealing with depth issues? A roundtable of fantasy analysts and NFL Nation reporters will join me to identify some choice names to consider each week.

Here are some of our favorites for Week 10:


Tua Tagovailoa, Miami Dolphins (31.7% rostered; vs. Chargers)

Was last week's awesome passing efficiency and nifty rushing against Arizona an outlier success for the rookie or a trend signaling a true fantasy sleeper? For those streaming each week at the position, Tua presents intriguing value given the Chargers have ceded the fourth-most fantasy points per game (21.5) to quarterbacks. Los Angeles entered the season with serious upside as a defensive group, but injuries and an underwhelming pass rush (ranked 16th in pressure rate) has allowed opposing passers to light up the scoreboard. -Jim McCormick

Running back

Duke Johnson, Houston Texans (68.0% rostered; at Browns)

If David Johnson misses this week's tilt with the Browns due to a concussion he suffered in Week 9, then firing up Duke Johnson in all formats will appear obvious to the fantasy market. In a revenge showdown with his former team, a Cleveland front yielding nearly 23 fantasy points per game to backfields in ESPN PPR formats, Duke makes for a reasonable plug-and-play in reception-driven formats, even if his peer Johnson is active. Deshaun Watson is peppering the line of scrimmage with targets since the team's coaching shift, as this Miami product has compiled nine receptions in the past two games. Such usage helps support a reasonable shot at double-digit fantasy production in PPR formats with room for much more if he's the featured option. -J.M.

J.D. McKissic, Washington Redskins (59.7% rostered; at Lions)

McKissic ranks third among RBs this season with 248 receiving yards and fourth with 34 receptions. And those rates have gone up when new Washington quarterback Alex Smith has been in the game. Smith entered Sunday's game in the final minute of the first quarter, and he went on to complete eight passes for 58 yards to McKissic the rest of the way. Now, Smith might not check down to the RB quite as much when he has a full week to practice the game plan, but McKissic was already a decent consideration as a bye-week replacement in PPR leagues. And this week's matchup is enticing for both McKissic and backfield mate Antonio Gibson against a Detroit Lions defense that has allowed the most fantasy points to RBs this season in both non-PPR and PPR leagues. -Mike Triplett, NFL Nation Saints reporter

Wide receiver

Darnell Mooney, Chicago Bears (16.9% rostered; vs. Vikings)

It's time. The King of the Air Yards is ready to post a big finish. Since Week 4, Mooney has been a top-40 receiver in air yards each week, but he has just one top-40 fantasy performance during that stretch. Of course, air yards don't always translate, but in the right spot they do and this is that spot with the Vikings allowing a league-high 16.3 yards per deep pass attempt. For the season, seven of the top 10 receivers in air yards per game are among the top-16 fantasy receivers on a per-game basis. Don't call it a #MondayNightMiracle, call it math. -Kyle Soppe, ESPN Fantasy researcher

Tim Patrick, Denver Broncos (14.9% rostered; at Raiders)

With Drew Lock often looking for Patrick down the field, it helps the wideout's case that the Raiders have ceded the fifth-most yards per catch (14.1) to the position on the season. With double-digit fantasy production in five straight outings and at least seven targets in three of his past four games, Patrick enters Week 10 as a quietly helpful streaming option amid one of the biggest bye weeks of the season at receiver. -J.M.

Tight end

Logan Thomas, Washington Football Team (18.5% rostered; at Lions)

Earning yet another endorsement in this column, Thomas, like Burton, continues to see a steady target rate as the premier move tight end for Washington. The fantasy lines aren't always stellar, but such steady usage -- Thomas has also been targeted at least four times in each appearance -- fosters the potential for rewarding fantasy results each time out. The Lions have been respectable in coverage against tight ends, but Thomas' opportunity rates can help him overcome the matchup. -J.M.

Defense/special teams (D/ST)

Philadelphia Eagles (77.5% rostered; at Giants)

The Birds' recent bye week served to depress this D/ST's roster percentage, even as Philly delivered a season-high 21 fantasy points against the Cowboys in Week 8. (Editor's note: This defense is among the most-added "players" this week, since this column originally published.) With another savory division matchup on the schedule, we can look to the precedent set by this defense in Week 7's tilt with the Giants that saw them post nine fantasy points. The key element to this recent stretch of defensive success is a revived pass rush, as the team has at least three sacks in three straight games and should again provide fantasy managers with a strong showing against a mistake-prone offense. -J.M.

Individual defensive players (IDP)

Defensive line

Romeo Okwara, Detroit Lions (4.4% rostered; vs. Washington)

An emerging lineman for the Lions, Okwara has contributed at least one sack or forced one turnover in five of his past six appearances. Facing a sloppy Washington offense this week could help Okwara sustain this pattern of big plays. -J.M.

Defensive back

Marcus Peters, Baltimore Ravens (8.8% rostered; at Patriots)

Deft in both run support and coverage, Peters has established himself as one of the best splash-play producers at his position. With at least one forced turnover in five outings this season and multiple turnovers in three of his past four appearances, this ball hawk is in a good spot to deliver fantasy value facing a subpar New England offense. -J.M.