Leitao was the Blue Demons' coach for three seasons from 2002 to '05. He took DePaul to one NCAA tournament, a round-of-32 finish in 2004, and two NITs. Leitao was 58-34 at DePaul.
He jumped to Virginia in 2005-06 but resigned after four lackluster seasons, a 63-60 overall record and only one NCAA tournament appearance.
Since then, Leitao has been an assistant at Missouri and Tulsa. He moved to the Golden Hurricane in 2014 when head coach Frank Haith made the same jump.
Leitao also was a head coach at Northeastern for two seasons in the 1990s, going 22-35 overall, between stints as an assistant under Jim Calhoun at Connecticut.
DePaul finished 12-20 (6-12 Big East) this season, leading to Oliver Purnell's resignation earlier this month.
ESPN's Andy Katz contributed to this report.