The Bulldogs cited a "violation of team rules" for Weatherspoon's discipline.
A starting guard for the team, Weatherspoon played 26 minutes in the Bulldogs' win over Alabama on Tuesday night, chipping in 6 points, 5 rebounds, 3 assists and 4 steals.
Weatherspoon's older brother, Quinndary, also starts for the Bulldogs.
Mississippi State (17-7, 5-6 SEC) plays at Arkansas at 8:30 p.m. ET tonight on the SEC Network.