The Huskers (4-8, 0-5 Big Ten) have now had five games postponed amid the pandemic.
Last week, Nebraska said coach Fred Hoiberg and 11 other staffers or players had tested positive for COVID-19. Hoiberg has an underlying health condition. He was born with an abnormal aortic heart valve and had to retire from pro basketball because of it in 2005.
For now, Nebraska's next scheduled game is Feb. 3 at Michigan State. Options for rescheduling the Penn State game will be discussed with the Big Ten Conference.