Wisdom launched a 1-1 slider from Austin Gomber over the left-field bleachers and onto Waveland Avenue for his 21st home run. He entered the year with four homers in 48 games over three seasons with the Cardinals, Rangers and Cubs.
Although he turns 30 on Friday, Wisdom still has rookie status. Cubs manager David Ross said Wisdom would get his vote for NL Rookie of the Year.
“I know Wiz is right there in the conversation,” Ross said while also mentioning Cincinnati's Jonathan India. “If I really had to vote, I'd vote for my guy.”
Wisdom struck out in his first two at-bats before taking Gomber deep.
“The third time you face a guy, you get a little more familiar with him," Ross said. “I think the power's real, 21 homers now. He knows he's going to punch out from time to time, but he works at it. He's doing a lot of good things at different moments."
Cubs starter Zach Davies said he's seen Wisdom make strides now that he's playing regularly.
“That's a guy in the lineup who can change the game,” Davies said.
Overall, Chicago is 4-3 following a 12-game skid.
C.J. Cron hit his team-leading 22nd homer for the Rockies, who have lost three straight following a five-game winning streak.
Davies allowed two runs on three hits and struck out six in 4 2/3 innings. The wiry right-hander went 0-4 with an 8.25 ERA in his previous five starts.
Gomber (9-8) allowed five runs on five hits in 4 2/3 innings. The lefty struck out eight and walked one.
“I thought he was fine, but the fifth inning came back to bite him," Rockies manager Bud Black said.
The twinbill was scheduled after Tuesday night’s game was rained out.
Cron homered to center off Davies’ 3-0 sinker with one out in the second to give the Rockies a 1-0 lead. Bote went deep to left in the bottom half to tie it.
Brendan Rodgers singled in a run in the third to put the Rockies back ahead, 2-1.
Romine lined his first homer in 13 games this season down the left-field line to tie it in the fourth.
The Rockies recalled INF Joshua Fuentes from Triple-A Albuquerque as the 27th man for the second game of the doubleheader. The Cubs recalled RHP Jake Jewell from Triple-A Iowa.
Rockies: LF Connor Joe collided hard with CF Sam Hilliard and dropped to the ground after Joe caught Frank Schwindel’s flyball in the first. Joe remained in the game after being checked by a trainer. He was back in the lineup in the leadoff spot for the second game. ... OF Raimel Tapia (toe sprain) will report to Triple-A Albuquerque this weekend for a rehab assignment and could return next week at Texas, Black said. Tapia has been on the 10-day injury list since Aug. 8.
Cubs: Ross doesn’t know when C Willson Contreras (sprained right knee) will be back behind the plate, but the two-time All-Star could be in the lineup as a DH this weekend against the crosstown White Sox.
Rockies RHP Germán Márquez (11-9, 3.80 ERA) faced Cubs LHP Justin Steele (2-2, 3.22) in the second game.