"I've always wanted to do what my dad did, ever since a young age, and finally here we've kind of switched roles,'' the younger Biggio said of his father, Craig Biggio. "He's in the seats now and I'm on the field. So that's pretty cool because it's everything I ever wanted.''
Cavan Biggio, who was playing in his third major league game Sunday, was 0-for-6 with three strikeouts before he singled to right field past San Diego Padres first baseman Wil Myers in the bottom of the second inning.
In the bottom of the fourth inning, he homered 405 feet into the upper deck in right field for his first major league home run.
He later singled to center in the bottom of the fifth for his third hit of the day and second RBI as he drove in Lourdes Gurriel Jr.
Biggio finished 3-for-4 with two RBIs in the Blue Jays' 10-1 victory.
"After I got that first hit, I felt like I could finally exhale and finally just play the game,'' Biggio said. "It was a big relief.''
Craig Biggio had 3,060 hits in his career. He started his career 0-for-7 before singling in his fourth career game, and he needed 33 games to hit his first home run, according to ESPN Stats & Information.
Cavan Biggio, who turned 24 in April, was hitting .306/.440/.507 with Triple-A Buffalo this season. He was selected in the fifth round of the 2016 draft.
The Associated Press contributed to this report.