Answering Week 1's biggest fantasy football questions

It's time to set your fantasy lineups for the first time this season. NFL Nation reporters answer the biggest fantasy questions -- provided by ESPN fantasy football analyst Mike Clay -- across the league for Week 1.

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Buffalo Bills

With Nathan Peterman under center, who can we trust to produce other than LeSean McCoy?

The most honest answer might be to trust nobody other than McCoy, but there are some reasons to take a gamble on WR Kelvin Benjamin. Peterman and Benjamin seem to have built a connection dating back to last season, when Peterman threw a touchdown to Benjamin in the snow against the Colts. In the preseason opener last month, four of Peterman's eight passes on the opening drive went to Benjamin, including a 28-yard touchdown. --Mike Rodak