Anthony Tuitavake was sent off as Racing 92 lost 23-19 at Agen in the Top 14.
La Rochelle climb into Clermont's buffer in the Top 14 standings as Zack Holmes kicks 20 points in 25-19 win over Toulouse.
A Ben Botica penalty three minutes into stoppage time saw Montpellier record a 12-11 victory over La Rochelle.
Edinburgh edged past Harlequins 36-35 in thrilling encounter in the European Challenge Cup.
- BRIV8thTries Scored 1st Lyon : 22 Tries ScoredLYON1st1222
- BRIV7thPoints Difference 1st Lyon : 81 Points DifferenceLYON1st-281