Zlatan Ibrahimovic will not feature in AC Milan's visit to Anfield to face Liverpool in the Champions League on Wednesday after he was left at home as a precaution following an Achilles' tendon strain.
"Ibrahimovic would have started," Milan manager Stefano Pioli told a news conference on Tuesday. "An inflamed tendon after four months out can happen.
"He was fine but after the match [on Sunday], he felt a little discomfort. This morning, he tried [to train], but he felt pain so there's need to take such a risk at this time of the season.
"Tomorrow's is a hugely important game, but we have so many more."
Asked whether an injury on the back of four months out meant Milan should start to imagine life without the striker, Pioli added: "I imagine Milan with Zlatan -- 100%. It's what he wants, what I want and what all his teammates want.
"With many other options. These [injuries] are part of the game but we are well prepared with [Ante] Rebic and Olivier [Giroud]. I feel for Ibra, who always wants to play to be in good shape."
Ibrahimovic helped Milan return to the Champions League for the first time since 2014 as his goals helped the Rossoneri to a second-place finish last season.
Former Chelsea forward Olivier Giroud, who missed Sunday's clash against Lazio despite testing negative for coronavirus after a period of quarantine, is in contention to start. The France international had started Milan's first two matches of the season, scoring two in the 4-1 win over Cagliari.
Ibrahimovic was in line for his first meeting with Liverpool since his late goal salvaged a 1-1 draw for former club Manchester United at Old Trafford in 2017.
This will be Milan's third-ever meeting with Liverpool, with their two previous encounters having come in the 2005 and 2007 Champions League finals with each side winning one apiece.
Milan travel to Juventus on Sunday in their next Serie A match.