Villarreal will face their coach Unai Emery's former club Arsenal in the last four after the English side overcame Slavia Prague.
Villarreal took a big step towards reaching the Europa League last four as the Spanish side defeated Dinamo Zagreb.
Manchester United will face Granada in the Europa League quarterfinals and could face Ajax or Roma should they reach the semifinals.
In this week's ESPN Insider Notebook, Barca eye Aguero should they fail to keep Messi. PLUS: Chelsea feel 'vindicated' over Lampard sacking.
The body of former Villarreal and Racing Santander striker Franco Acosta has been found in a creek two days following his disappearance.
Valencia scored twice in the last five minutes through Carlos Soler and Goncalo Guedes to beat visiting neighbours Villarreal 2-1.
Atletico Madrid secured a vital 2-0 win away to Villarreal on Sunday to reaffirm their title ambitions following a difficult run of results.
Real Madrid are monitoring central defensive options as the uncertainty around the future of Sergio Ramos grows. Transfer Talk has the latest.
Samuel Chukwueze expects to miss Nigeria's final two games of the 2021 Africa Cup of Nations qualifying campaign after undergoing groin surgery.
Villarreal drew 2-2 at home to Granada on Wednesday to return to fourth in La Liga but will be kicking themselves for not taking all three points.
La Liga leaders Real Sociedad's six-game winning streak ended on Sunday as they were held to a 1-1 draw at home to Villarreal.
Atletico Madrid have a great opportunity to win La Liga for the first time in seven years. If they fail to take it, they'll regret it forever.
Real Madrid were pegged back in the second half to draw 1-1 against Villarreal, having taken the lead through Mariano Diaz.
Villarreal midfielder Dani Parejo scored the decisive goal in a 2-1 win at home to former club Valencia to take his side top of La Liga on Sunday.
Unai Emery's embarrassingly over-conservative approach to Take Kubo's game time at Villarreal has to stop. The Japan star needs a chance to shine.
Atletico Madrid drew 0-0 at home to Villarreal on Saturday in La Liga for a second consecutive goalless draw.
Barcelona coach Ronald Koeman says Lionel Messi has been the ideal captain and an example to the rest of the team for the way he has applied himself
Atletico Madrid coach Diego Simeone has backed forward Joao Felix to show his best form this season after an up and down debut campaign in the Spani
Teenage forward Ansu Fati scored twice in Barcelona's opening La Liga game of the season.
"That ability to dribble, to feint, to strike the ball...that the Mexican player has is more difficult for us [in Europe]," Herrera said.