Once-great Penarol is out of Copa Lib, but Flamengo, Boca Juniors and River Plate ensure plenty of intrigue left in round of 16.
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The Uruguayan Primera Division features an awkward assortment of 15 clubs, which is symbolic of the challenges football clubs face in the country.
The San Jose Earthquakes have signed Penarol's Yeferson Quintana on a year-long loan with an option to buy.
Los Angeles FC is on the verge of signing Penarol striker Diego Rossi Marachlian, sources have confirmed to ESPN FC.
Manchester United have confirmed that defender Guillermo Varela has re-joined former club Penarol.
"We hope CONMEBOL [South American Football Confederation] will take action," Palmeiras president Mauricio Galiotte said.
After two weeks of Copa Libertadores battle, the Brazil clubs look likely to win the title but the Argentina clubs may just catch up.
Barcelona have confirmed the signing of teenage defender Santiago Bueno from CA Penarol.
The Uruguayan Football Association postponed all matches in the country this weekend following the death of a Penarol fan.
Diego Forlan has said that he will play for Mumbai City in a three-month deal.
"I called him on Saturday to ask him to come back to Penarol," Damiani said of Forlan.
Preseason friendlies rarely end in managers losing their jobs but that was the case after Penarol lost to Nacional, writes Tim Vickery.
"I still have not had an offer to come but we'll see," said Diego Forlan of a potential MLS move.
Iker Casillas' Real Madrid exit and his signing with Porto was "a step back for Iker," said Uruguay striker Diego Forlan in his weekly column.
Uruguayan striker Diego Forlan has signed with Uruguayan Primera Division side Penarol, where he played as a boy, the club announced on Friday.
They've been rivals since 1900. On Sunday, one of them could clinch a title with a victory. Tim Vickery on the latest meeting between the big two teams in Montevideo, Uruguay.