Tigres UANL avoided a massive upset in Concacaf Champions League thanks to a stoppage time goal scored by goalkeeper Nahuel Guzman.
MLS record-breakers LAFC will face a stern CONCACAF Champions League debut, after being drawn against Liga MX's Club Leon in the round of 16.
New York Red Bulls set up an MLS-Liga MX clash with Santos Laguna as both sides advanced in the CONCACAF Champions League match.
An own goal and a Daniel Royer tally gave NYRB a 2-0 win over Atletico Pantoja in the first leg of their CCL opening-round series on Wednesday.
Liga MX side Tigres have sealed their progress from CONCACAF Champions League Group G with a 3-0 win over Herediano on Tuesday night.