The geographic proximity of the fan bases -- and their cultural links -- provide the backdrop of what is arguably Germany's most passionate derby.
Bayern Munich will be without winger Serge Gnabry for their Champions League game against Atletico Madrid after he tested positive for COVID-19.
RB Salzburg boss Jesse Marsch has said Frank Lampard did not rate Christian Pulisic at the start of his Chelsea career because he was American.
Schalke 04 came from a goal down to snatch a 1-1 draw against visitors Union Berlin on Sunday, snapping their six-game losing run in the Bundesliga.
Frankfurt missed the chance to go top of the Bundesliga on Sunday, settling for a 1-1 draw at Cologne to stay two points behind leaders RB Leipzig.
Bayern Munich's Robert Lewandowski and Thomas Muller scored two goals each as the German champions crushed hosts Arminia Bielefeld.
Borussia Dortmund needed a second-half goal by substitute Marco Reus to beat Hoffenheim 1-0.
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