Paris Saint-Germain clung on to their hopes of winning a fourth consecutive Ligue 1 title with a 4-0 home win against 10-man Stade de Reims as Lille's lead was cut to a single point with one game remaining on Sunday.
As PSG cruised to a routine victory, Lille, who have 80 points, were held to a goalless draw by mid-table St Etienne and now need a win at Angers in the final round to guarantee them a first title since 2011.
They lead fourth-placed Olympique Lyonnais, in the first of two Europa League spots, by one point after Rudi Garcia's team secured a 5-2 win at Nimes thanks to a double by Lucas Paqueta and goals by Memphis Depay, Houssem Aouar and Islam Slimani.
Second-from-bottom Nimes were relegated to Ligue 2.
Olympique Marseille, on 59 points, occupy the other Europa League spot in fifth place as Arkadiusz Milik's hat-trick gave them a 3-2 win against Angers, while RC Lens (56) are sixth following a 3-0 loss at Girondins de Bordeaux.
At the Parc des Princes, PSG were never troubled by a Reims side who played most of the game with 10 men in a warm-up before Wednesday's French Cup final against Monaco.
Lille lacked inspiration against a sturdy St Etienne side and missed out on securing a victory that would have allowed them to head into the final round needing only a draw when Yusuf Yazici's free kick crashed onto the far post in the last minute.
"The way St Etienne played today, I had never seen them play like this but it is what it is, it was up to us to be better," said Lille captain Jose Fonte.
"We're now going to focus on next Sunday to win that final."