Ronald Koeman's men were shocked by the Norwegian club and are out of the Europa League, while a Marco Reus hat trick put BVB into the group stage.
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Borussia Dortmund rallied from a shocking three-goal deficit to win 4-3 at Odd Grenland in the Europa League playoff round first leg on Thursday.
Ludogorets Razgrad's Champions League dreams came to an early end on Tuesday as they bounced out of the competition in the second qualifying round.
Two of last season's Champions League group-stage underdogs got off to a rough start in the first leg of the second qualifying round on Tuesday.