LA Galaxy defender Julian Araujo and Arsenal academy youngster Marcelo Flores made their Mexico debuts in a 2-2 draw against Chile.
With Brazil into the World Cup and Argentina on the verge, teams such as Ecuador, Colombia, Chile, and Uruguay are fighting for their spots.
It sounds like a dream: a kid from England ends up playing against Lionel Messi in the Copa America. But there's so much more to it than that.
Chile are still reliant on old stalwarts like Arturo Vidal and Alexis Sanchez, but England-born Ben Brereton Diaz gives 'La Roja' the best chance.
Chile and Bolivia have the chance to get back into World Cup contention with two crucial home games over the next few days.
Brazil are leading the way in CONMEBOL qualifying, but what about the rest as this week's tripleheaders see two-thirds of games complete?
The suspension of Argentina vs. Brazil took the spotlight off a competitive South American World Cup qualifying, but all eyes are back on the pitch.
South American players are in a club-vs.-country tug of war, a situation made worse by CONMEBOL's insistence on playing this year's Copa America.
Everton Ribeiro came off the bench to score the goal that gave Brazil a barely deserved 1-0 win over Chile on Thursday.
Brazil are comfortably out front of South America's World Cup qualifying campaign, but behind them, a lot could change between now and Qatar 2022.
Brazil midfielder Lucas Paqueta helped his side beat Chile, while Peru overcame Paraguay on penalties.
Brazil beat Chile in their quarterfinal match at the Copa America on Friday night despite playing the majority of the second half with 10 players.
Will Neymar lead Brazil to another Copa America crown, or will Lionel Messi finally win his first senior international title with Argentina?
Neymar is in form, Leo Messi is breaking records, but it's the displays of Ricardo Gareca's Peru that have been the talk of the Copa group stage.
Miguel Almiron got a goal and an assist as Paraguay beat Chile 2-0 in the Copa America on Thursday and confirmed their place in the last eight.
Uruguay's Facundo Torres and Ecuador's Gonzalo Plata may be inconsistent, but they are making people sit up and take notice at the Copa America.
Chile's Arturo Vidal put through his own net to give Uruguay their first goal in five games and grant them a point in a 1-1 Copa America draw.
There were 140 known COVID-19 cases at the Copa America in Brazil on Monday, up from 66 positive tests on Thursday.
A number of Chile's players will be fined after inviting a barber into their Copa America bubble, thereby breaking strict coronavrius protocols.
Chile secured a 1-0 win over Bolivia with a goal from English-born striker Ben Brereton in their Copa America clash on Friday.
The second set of Copa America matches saw Argentina get their first win of the tournament while hosts Brazil scored another big victory.
Half of the teams playing the Copa America -- Venezuela, Bolivia, Colombia, Peru and Chile -- have confirmed at least one positive test.
The first set of Copa America matches have concluded. As Brazil still struggles with COVID-19 cases, the on-field action is officially underway.
Lionel Messi scored for Argentina, but Chile answered in the second half as the sides played to a 1-1 draw in the group stage at the Copa America.