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Barcelona dominated possession throughout Sunday's match at Camp Nou, the first for Quique Setien since taking over for Ernesto Valverde last week.
Atletico Madrid lost ground on leaders Barcelona as they were held 1-1 away to Granada on Saturday for a seventh draw in 14 La Liga games.
Real Sociedad went level on points with La Liga leaders Barcelona after snatching a 2-1 victory away to fellow high-flyers Granada on Sunday.
Granada missed a chance to extend their fairytale start to the season and return to the top of La Liga as they fell to a 3-1 defeat at Getafe.
Granada were promoted last season and top the table after 10 weeks. What does that say about them and the likes of Barca and Real Madrid?
Promoted Granada continued their stunning start to the season by climbing above Barcelona to the top of La Liga on Sunday after beating Real Betis 1
Granada provisionally climbed into second place in Spain's La Liga on Friday after edging past visitors Osasuna 1-0 courtesy of Domingos Duarte.
Eden Hazard scored his first goal for Real Madrid as they beat Granada 4-2 at the Bernabeu on Saturday to remain top of La Liga.
Promoted Granada moved into first place in La Liga after a convincing 2-0 win over Barcelona on Saturday took them to 10 points.
Andreas Pereira says he is a better player for working under Tony Adams at Granada and is more confident than ever of kicking on at Manchester United.
"I signed a four-year deal [in 2016] and I know the club have faith in me. The idea was to spend a year away on loan," Samper said.
Ochoa, who spent last season on loan at Granada from Malaga, becomes a free agent next month.
Guillermo Ochoa: "I want to thank the fans for their unconditional support throughout this year. They made my stay a pleasant one."
Granada slumped to a seventh straight defeat under manager Tony Adams, losing 2-1 at home to Espanyol in their final match of the season.
Granada interim manager Tony Adams says he "will not go away" after failing to keep his side in the top flight this season.
Real Madrid swept past relegated Granada 4-0 with a clinical first-half display at Los Carmenes to move back level with La Liga title rivals Barcelona
Granada are relegated, Jonathan dos Santos produced another assist, and Real Sociedad are closer to a Europa League position. Mexicans in Europe.
Caretaker boss Tony Adams saw his Granada side relegated from LaLiga after suffering a 2-1 defeat at Real Sociedad.
Adams saw Granada slump to a third straight defeat since he took over when Malaga beat them 2-0 at home on Tuesday.
Ivory Coast have confirmed that Jeremie Boga and Jean-Philippe Gbamin have committed their international futures to the Elephants.