ROME -- Four-time champion Serena Williams withdrew from the upcoming Italian Open, citing the Achilles issue that bothered her in a loss to Victoria Azarenka in the US Open semifinals, organizers at the Foro Italico announced Saturday.
Williams took a medical timeout for a tape job on her Achilles tendon during her three-set loss on Thursday.
"I regretfully must withdraw from the [Italian Open] due to an Achilles strain," Williams said. "I'm so humbled by the continuous support from my fans in Rome and I look forward to making my return soon."
The Italian Open, which was rescheduled from May because of the coronavirus pandemic, begins Monday.
Azarenka remained entered for Rome.
Nine-time champion Rafael Nadal headlines the field in the Italian capital, marking his return to tennis after a seven-month layoff. The Spaniard has been practicing in Rome for several days.
Top-ranked Novak Djokovic, who was disqualified from the US Open, is also entered.
The clay-court tournament in Rome is a warm-up event for the French Open, which starts Sept. 27.