This week, ESPN fantasy guru Matthew Berry, betting analysts Anita Marks, Eric Moody and Joe Fortenbaugh, sports betting deputy editor David Bearman, ESPN Stats & Info's Seth Walder, along with Football Outsiders' Aaron Schatz, offer their best bets.
Odds courtesy of Caesars Sportsbook as of Sunday, unless otherwise noted.
Arizona Cardinals at Los Angeles Rams (4, 49.5)
Schatz: My pick in this game is driven by weighted DVOA, focusing on how well teams have played over the last nine to 10 weeks instead of the entire season. The Cardinals had a strong 37-20 win over the Rams in Los Angeles, but that was way back in Week 4. Things have changed since then. Personnel has changed. The Cardinals, most importantly, no longer have DeAndre Hopkins. The Rams have added Von Miller and exchanged Robert Woods for Odell Beckham Jr.