After holding the Lions to three-and-out to start, the Redbirds (3-1) used a 10-play, 65-yard drive to get on the board when Mueller ran it from the 5 for a 6-0 lead as the point-after attempt was blocked.
Following another Lindenwood three-and-out, Illinois State drove 61 yards in 11 plays and ended when Annexstad completed an 11-yard scoring pass to Eddie Kasper.
Lindenwood responded after recovering an Illinois State fumble got on the board when Robert Giaimo ran it in from the 3 to end a 12-play, 67-yard drive.
The Redbirds countered on their next drive when Annestad threw a 62-yard scoring pass to Daniel Sobkowicz for a 20-7 lead. Undeterred, Lindenwood responded when Cole Dugger threw a 73-yard touchdown to Jeff Caldwell to close first-half scoring.
Illinois State emerged from the break with their play-chewing ways and rolled 72 yards in nine plays and scored when Mueller ran it in for a 27-14 lead.
Dugger threw for 192 yards for Lindenwood (2-2).
AP college football: https://apnews.com/hub/college-football and https://apnews.com/hub/ap-top-25-college-football-poll