The No. 12-ranked Crimson Tide (3-1, 1-0) travel to face the Bulldogs (2-2, 0-2) on Saturday at 9 p.m. ET.
Lawson was sidelined during last weekend's win over Ole Miss with what Saban said was a "pretty good" ankle sprain. He has not been able to practice.
Lawson, a redshirt sophomore from Mobile, has 26 tackles, 2 sacks and 2 quarterback hurries.
The Tide could also be without reserve offensive lineman Terrence Ferguson, who left Saturday's game with an injury.
Like Lawson, Saban said Ferguson is very questionable.