Lecce staged a second-half comeback to beat Lazio 2-1 at home on Wednesday, inflicting a second Serie A defeat in a row on Maurizio Sarri's side.
Ciro Immobile, who was making his first start since October after returning from a hamstring injury, put the visitors ahead after 14 minutes when he received a through ball inside the box and finished into the far-left corner.
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Lecce equalised in the 57th minute when Gabriel Strefezza was first to the ball after Lazio keeper Ivan Provedel had blocked a shot and he finished into the empty net.
Lorenzo Colombo completed the comeback in the 71st minute after being left unmarked inside the box to tap the ball home from a cross.
Lazio mounted a late push to get an equaliser, but could not find an opening against a defensive Lecce.
The result left Lazio fifth in the standings with 30 points from 16 games, while Lecce are 13th with 18 points.
"If we don't beat Lecce it means that, perhaps, we are inferior to what we think we are. They upped the tempo when we allowed them to, when they saw us vulnerable they were very good at biting and tearing us apart," Sarri added.