- Sandi Lovric (13')
- Victor Osimhen (52')
The result ended the city's long wait for the Scudetto since Argentine great Diego Maradona led them to two championships in 1986-87 and 1989-90.
Napoli have 80 points, securing their position at the top of the table. Second-placed Lazio, who also have five games left to play, are 16 points adrift of Napoli.
Visiting supporters at the capacity Stadio Friuli held aloft banners adorned with the image of the late Maradona, eagerly anticipating the long-coveted Scudetto.
Sandi Lovric dampened the spirits of Napoli fans when he scored the opening goal after 13 minutes, with a well-placed shot that found the top-right corner of the box.
In the 53rd minute, Osimhen sparked jubilant celebrations among the visiting fans when he fired in the equaliser from a rebound.
As the final whistle blew, Napoli supporters rushed onto the pitch to celebrate the momentous occasion alongside the players.
- Rosario Abisso